Cristom cultivates eight vineyards growing Pinot Noir, Chardonnay, Pinot Gris, Viognier and Syrah totaling 65 plantable acres. The vineyards are dry farmed with the focus on quality fruit with low yields and high density planting. Cristom's vineyards are named for family matriarchs. "The six ladies" each have natural variances in soil and elevation and the grapes they nurture were selected to highlight each vineyard's distinct attributes.

The tasting room is located in the Eola Hills with a view of Mount Jefferson.